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(2021) 22:e51981
doi:10.1007/s00394-014-0706-z Shimizu H, Kiyohara Y, Kato I, et al
(Official FDA prescribing information: confirms the 6-step titration 2.5 to 15mg in 2.5mg increments every 4 weeks, once-weekly subcutaneous administration, 15mg maximum dose for chronic weight management.) U.S
A 500mg capsule with 5% absorption is far less effective than a 100mg dose with 90% absorption
Lending support to this hypothesis, a recent imaging study demonstrated that GLP-1 reduces activity in parts of the brain involved in appetite and reward in people with Type 2 diabetes and obesity
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